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Chemistry of nucleic acids

By: Material type: TextLanguage: English Publication details: Boston : De Gruyter, 2024.Edition: Rev. 2nd edDescription: xii, 398p. : col. ill. ; 24 cmISBN:
  • 9783111325323
Subject(s): Other classification:
  • E1:8:3N R4
Summary: Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function.
Item type: Textual
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Textual Central Science Library Central Science Library E1:8:3N R4 (Browse shelf(Opens below)) Available SL1656252

Includes references and index

Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function.

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