Essential Biochemistry, 5th edition, comprises biology, pre-med, and allied health topics and presents a broad, but not overwhelming, base of biochemical coverage that focuses on the chemistry behind biology. This text relates the chemical concepts that scaffold the biology of biochemistry, providing practical knowledge and many problem-solving opportunities to hone skills. Key Concepts and Concept Check features help students identify and review important takeaways in each section. This international adaptation contains up-to-date coverage of topics, including Ramachandran diagrams, lysozymes, steroid hormones, and ionophores. It also offers integrated coverage of SARS-CoV-2 and the impacts of COVID-19, relating it to the importance of an interdisciplinary response to a global pandemic. By focusing on strengthening the organization of the content as well as updating the end-of-chapter problems, this edition presents a brand-new experience to the reader.