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008			220909b |||||||| |||| 00| 0 eng d
020			_a9780815344469
037			_cTextbook
040			_aCSL _beng _cCSL
041			_aeng _2eng
084			_aE9G,92Z2 Q2 TI _qCSL
100			_aWilliamson, Mike _eauthor. _9463643
245		0	_aHow proteins work
260			_aNew York : _bGarland Science, _c2012.
300			_axv, 464p. _b: ill. _c; 28 cm.
500			_aGlossary 435-444p.; Index 445-464p.
520			_aHow Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. This text will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics. It will also serve as a valuable resource for graduate students and researchers looking for a reference on the fundamentals underlying protein function. By providing an integrated view of proteins at both a cellular and systemic level, this textbook shows how evolution drives proteins to adopt domain structures that combine to achieve biological outcomes. The association of proteins into dimers, molecular machines, and multi-enzymatic complexes enables them to achieve catalytic and functional efficiency.
650			_a Proteins flexibility _9811773
650			_a Proteins interactions _9811774
650			_a Proteins work _9811775
650			_aZoology
942			_hE9G,92Z2 Q2 TI _cTB _2CC _n0
999			_c14053 _d14053