000 01389cam a22002775i 4500
001 23680486
005 20250626105731.0
008 240508s2024 mau 000 0 eng
020 _a9783111325323
040 _aCSL
_cCSL
041 _2eng
_aeng
084 _aE1:8:3N R4
_qCSL
100 1 _aLönnberg, Harri
_eauthor.
_9814681
245 1 0 _aChemistry of nucleic acids
250 _aRev. 2nd ed.
260 _aBoston :
_bDe Gruyter,
_c2024.
300 _axii, 398p.
_b: col. ill.
_c; 24 cm.
500 _aIncludes references and index
520 _aLife in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function.
650 _aNucleic acids.
_9582160
650 _aDNA.
_9449427
650 _aRNA.
650 _aNucleotides.
_9814682
650 _aMolecular biology.
_9414923
942 _2CC
_cTEXL
_eRev. 2nd ed.
_hE1:8:3N R4
_n0
999 _c1432983
_d1432983