000			02174nam a2200301Ia 4500
003			OSt
005			20250830122000.0
008			220909b |||||||| |||| 00| 0 eng d
020			_a9780470712368
037			_cTextual
040			_aCSL _beng _cCSL
041			_aeng
084			_aE5:4, M2;P8;24 _qCSL
100			_aWarren, Stuart _eauthor
245		0	_aOrganic synthesis: the disconnection approach
250			_a2nd ed.
260			_aWest Sessex: _bWiley, _c2008
300			_aviii, 329p. _b: ill.
500			_aIndex 325-329p.
520			_aIntroduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, “Organic Synthesis: Strategy and Control”. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry.
650			_a Disconnections _9819477
650			_a Strategy _9819478
650			_aTwo group _9819479
700			_aWyatt, Paul _eco-author
942			_hE5:4, M2;P8;24 _cTEXL _2CC _n0
999			_c16803 _d16803