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020 _a9780815345565
037 _cTextual
040 _beng
_aCSL
_cCSL
041 _aeng
084 _aLZ3:(E) Q8 TL
_qCSL
100 _aDunlap, Norma
_9859774
245 0 _aMedicinal chemistry
260 _aNew York,
_bCRC press:
_c2018.
300 _axii, 495p.
_b: ill.
500 _aGlossary 467-476p.; Index 477-495p.
520 _aMedicinal Chemistry teaches essential concepts by focusing on how the field is actually practiced, melding real-world research experience with basic principles and modern methods. Written by practicing medicinal chemists, this textbook is intended for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry. Pre-medical or pre-pharmacy students and professionals entering the drug discovery field will also find it a useful reference. Building on a foundation of synthetic organic chemistry and structural biology, the book interweaves therapeutics, case studies, historical context, and techniques for discovering, developing, and optimizing new drugs. Chapters are richly illustrated and include problems and annotated journal references with accompanying exercises and answers. Authored by practicing medicinal chemists―melding real-world research experience with basic concepts and up-to-date methods Flexible in presentation― the first five chapters provide a conceptual foundation and historical understanding of the field; subsequent chapters explore the application of concepts. Chapters can be assigned in order of instructor preference and desired emphasis Presents easy-to-follow tables and descriptions of assays next to their relevance to medicinal chemistry and drug discovery, along with target values―information rarely found all in one place, but is a crucial reference Case studies and Journal Club use current literature to apply concepts from the text to real-life examples. They are also suitable for flipped classrooms and self-study.
650 _a Drugs
_9859775
650 _a Medicine
_9859776
650 _a Protein
_9859777
650 _aChemistry
_9859778
700 _aDunlap, Norma
_9859774
700 _aHuryn, Donna M.
_9859779
942 _hLZ3:(E) Q8 TL
_cTB
_2CC
_n0
999 _c3356
_d3356